Dialysate sodium, serum sodium and mortality in maintenance hemodialysis

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Dialysate sodium, serum sodium and mortality in maintenance hemodialysis.

BACKGROUND Individuals with end-stage kidney disease appear to have stable pre-dialysis serum sodium concentrations over time, with lower values associating with increased mortality. Dialysate sodium concentrations have increased over many years in response to shorter treatments, but the relationship between serum sodium, dialysate sodium and outcomes in chronic hemodialysis patients has not ye...

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Dialysate sodium and sodium gradient in maintenance hemodialysis: a neglected sodium restriction approach?

BACKGROUND A higher sodium gradient (dialysate sodium minus pre-dialysis plasma sodium) during hemodialysis (HD) has been associated with sodium loading; however, its role is not well studied. We hypothesized that a sodium dialysate prescription resulting in a higher sodium gradient is associated with increases in interdialytic weight gain (IDWG), blood pressure (BP) and thirst. METHODS We co...

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Effect of dialysate sodium concentration and sodium gradient on patients with maintenance hemodialysis

Backgrounds: Patients with maintenance hemodialysis (MHD) have a high risk of cardiovascular disease, which is the leading cause of morbidity and mortality. The aim of the present study was to explore the relationship between the sodium gradient and the water load of MHD patients. Methods: Eighty one MHD patients were selected in the study. The serum sodium concentration, sodium gradient, inter...

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Sodium Balance in Maintenance Hemodialysis

Sodium is the principal solute in the extracellular compartment and the major component of serum osmolality. In normal persons in the steady state, sodium homeostasis is achieved by a balance between the dietary intake and the urinary output of sodium, whereas in intermittent hemodialysis patients, sodium balance depends on dietary intake and sodium removal during hemodialysis. Thus, the main g...

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Clinical Effects of Standard and Individualized Dialysate Sodium in Patients on Maintenance Hemodialysis

BACKGROUND The degree to which the dialysate prescription and, in particular, the dialysate sodium concentration influences blood pressure and interdialytic weight gain (IDWG) via changes in sodium flux, plasma volume or the other parameters is not well understood. The aim of the study was to investigate whether dialysis patients will have some beneficial effects of dialysate sodium set up acco...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2011

ISSN: 0931-0509,1460-2385

DOI: 10.1093/ndt/gfr497